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J Postgrad Med J

Gpxs exist in multiple isoforms, with different cellular localization and different substrate specificity ( 2 O 2 , Prxs seem to be more active, given their higher intracellular concentration and rate constant ( GSH, exploiting the redox-active thiol residue (-SH) of cysteine, exerts its antioxidant function mainly via Gpxs-mediated reactions, which result in peroxide buffering with simultaneous oxidation of GSH to GSSG ( Besides the neutralization of free radicals produced in phase 1 liver metabolism of chemical toxins, GSH also participates in the protection from the resulting electrophilic substrates through the intervention of glutathione-S-transferases (GSTs)

Alcohol, inflammation, and microbiota in alcoholic liver disease

If an anaphylactoid reaction (rash, hypotension, wheezing, dyspnea, or any dermatologic manifestations other than flushing and erythema) occurs during IV acetylcysteine therapy, the drug should be temporarily interrupted in order to administer antihistamines and, in severe reactions, epinephrine

The virus-containing medium was harvested after 48 h, after which cells were infected with virus and 1 g/mL polybrene