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In addition, (native) CRP can affect IL-6-mediated inflammatory events by enabling the formation of the sIL-6R/IL-6 complex [115]

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Science 257:12481251 Muceniece R, Zvejniece L, Vilskersts R, Liepinsh E, Baumane L, Kalvinsh I, Wikberg JE, Dambrova M (2007) Functional evaluation of Thiq, a melanocortin 4 receptor agonist, in models of food intake and inflammation

It is also used to treat a variety of conditions such as Alzheimer's disease, age-related memory loss, depression, and nerve pain