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Genetics (2009) 182(2):56574

Tirzepatide: GLP-1 + GIP (Dual Agonist) Tirzepatide activates two receptors

Other side effects are very rare

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For example, ROS is produced in several ways in the mitochondria, and succinate oxidation is one of the ways to generate ROS during NAD-linked substrates, such as coupled respiration with succinate in complex I via reverse electron transfer from complex II to I
Loddenkemper C, Keller S, Hanski M-L, et al