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Despite this, a prolonged adaptive immune response is the hallmark of effective viral eradication

Its broader receptor activity underlies systemic side effects: pronounced nausea, vomiting, flushing, increased blood pressure, spontaneous and sometimes painful erections (priapism), and altered mood or libido

By regulating energy balance through AMPK activation and mitochondrial signaling, it offers potential benefits for metabolic health, fat loss, endurance, recovery, and aging

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The classic hospital KD protocol involves a 2448-h fast to induce metabolic ketosis, after which the KD ratio is gradually increased, starting with a 1:1 ratio (1 g of fat per 1 g of protein and carbohydrates), until a 4:1 ratio is achieved (61, 64, 65)