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doi: 10.1016/j.ebiom.2016.04.002

found that downregulation of ALPK1 expression in HK-2 cells reversed the upregulation of high glucose-induced expression of cellular pyroptosis-related proteins and the increase of cellular pyroptosis ( In summary, initially, inflammatory cytokines function locallyeither affecting neighboring cells (paracrine) or acting on the same cells that produce them (autocrine)to initiate the epithelial-to-mesenchymal transition in the kidneys

Dolan L, Willemsen KV, Linstead PPS, Roberts K, Scheres B (1993) Cellular organisation of the Arabidopsis thaliana root

Xu Zhao et al., effectively employed trichothecin to trigger necroptosis in cancers that are resistant to chemotherapy

Regulation of and challenges in targeting NAD+ metabolism