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This can compromise mitochondrial membrane integrity and DNA, affecting normal ocular tissue function in TAO ( Inflammatory response: Oxidative stress promotes persistent inflammatory reactions that contribute to ocular tissue damage in TAO ( Mitochondrial oxidative stress likely plays a significant role in TAO pathogenesis by influencing thyroid function, damaging ocular tissues, and perpetuating inflammation

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The effect of okra against DM and CD may also be caused by the presence of abscisic acid rather than simply okra polysaccharides, but further research into the mechanisms of action is necessary (Zhu et al., 2020)

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Indeed, Lcn2 knockdown via shRNA restored mitochondrial membrane potential, as evidenced by increased JC1 fluorescence (Fig