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Although xCT by itself does not seem to significantly influence the survival or proliferation of glioblastoma cells, its involvement in the secretion of Glu by these cells has been indisputably documented in experiments with siRNA [58] (Fig

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Male mice were administered a combination of 8 international units (IU) IN-insulin, 5 g IN-exendin, in a solution containing 2 mM of L-penetratin, a cell-penetrating peptide designed to boost the uptake of both therapeutic agents, or placebo, daily for 30 days

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