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Vegetarian and vegan diets and the risk of cardiovascular disease, ischemic heart disease and stroke: a systematic review and meta-analysis of prospective cohort studies

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Conditions that may affect the results of susceptibility testing of Mycobacterium tuberculosis to pyrazinamide

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(2018) demonstrated a gut-brain signaling axis in a mouse model of NEC in which activation of intestinal TLR-4 signaling led to release of high-mobility group box 1 (HMGB1) protein in the intestine, which in turn, promoted activation of TLR-4 on brain microglial cells resulting in accumulation of reactive oxygen species, loss of oligodendrocyte premature cells, dysmyelination, and cognitive impairment

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Paradoxically, this is accompanied by a BDNF-TrkB-mediated upregulation of synaptic GABA A Rs and by an 1-to-2GABA A R subunit switch, providing a mechanistic rationale for the analgesic action of the 2,3GABA A R benzodiazepine-site ligand L838,417 after nerve injury

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Data export and spectral visualization were performed using MestRenova 12.0.0 (MestreLab Research, Santiago de Compostela, Spain), with median values reported and normality assessed via the KolmogorovSmirnov test [27], [28], [29], [30], [31]

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MRX34, a miR-34a mimic, was developed to assess its safety, pharmacokinetics, and pharmacodynamics in a Phase I trial (NCT01829971)

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