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In a previous report, 2-week administration of pefloxacin (900 mg/kg/day) to rats caused the emergence of tenocytes with round nuclei in Achilles tendons ( Biomechanical examination Biomechanical examination of the rats was performed using a tensile testing machine (MODEL-1310VRW, Aikoh Engineering, Osaka, Japan)

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6.3 Metabolism 6.3.1 Animal studies The main pathway for the metabolism of acetaldehyde is shown in Fig

[PubMed: 3776973] 226
