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PGRMC1 dimerization is required for binding to EGFR Because PGRMC1 is known to interact with EGFR and to accelerate tumour progression 18 , we examined the effect of haem-dependent dimerization of PGRMC1 on its interaction with EGFR by using purified proteins

dispose in a sharps container immediately after use

LPS (tlrl-eblps), nigericin (tlrl-nig), monosodium urate (MSU) crystals (tlrl-msu) and zymosan (tlrl-zyn) were from Invivogen

Thats exactly why so many in-vitro experiments use fibroblast cultures as their starting point when studying this compound