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Indeed, an experimental observation has verified that LGS promotes genetically induced autoimmunity

A deficiency in Slc2a1 (encoding the Glut1 protein) reduces the number of thymocytes, inhibits the expansion of effector CD4 + T cells, and diminishes cytokine production across various CD4 + T cell subsets, including interferon-gamma (IFN), interleukin-4 (IL-4), and interleukin-17 (IL-17)

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10.3390/ph15080975

Rectal burn caused by hot-water coffee enema

Further mechanistic data is needed along with large randomized controlled trials in select populations of sick children, who may eventually benefit from supplemental Gln