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They also modulate DNA repair pathways, adjusting their activation in response to oxidative stress, ensuring efficient DNA damage repair and minimizing mutation accumulation [73]

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doi: 10.2174/0929867329666220322110348 178 ForouzandeRGharehaghajiAAMohammadiD

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For instance, the application of MDA-MB-468 in TNBC xenograft models has confirmed the inhibitory effect of IMMU-132, an antibody-drug conjugate targeting Trop-2, on tumor growth