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In contrast, L-carnitine has been shown to activate mTOR signaling in the skeletal muscle of rats ( via the phosphoinositide 3-kinase (PI3K)/Akt/mTOR pathway (Yoshida and Delafontaine, 2020)

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Acetyllevocarnitine hydrochloride for the treatment of diabetic peripheral neuropathy: a phase 3, randomized clinical trial in China

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[DOI] [PMC free article] [PubMed] [Google Scholar] [152].Edwards YH, Chase JF, Edwards MR, Tubbs PK

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10.1186/s12864-021-07576-4 220 ZongY.LiH.LiaoP.ChenL.PanY.ZhengY.et al (2024)

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[PMC free article] [PubMed] [Google Scholar] 199.Mak K.M., Chen L.L., Lee T.F

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Psychosocial impact and challenges of living with TMAU: Those who are affected often feel embarrassed and ashamed, struggle to maintain relationships, avoid others who make remarks about their illness, and become obsessed with smoking and using personal hygiene items to mask the smell [6,9,28]

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