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References 1.Steere AC, Grodzicki RL, Kornblatt AN, Craft JE, Barbour AG, Burgdorfer W, et al

Reduced Acidic Reabsorption : Sodium and potassium bicarbonates buffer hydrogen ions, reducing the reabsorption of acidic compounds like ammonium and chronic low grade acid-forming conditions

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This increased expression mediates enhanced intracellular glutamate efflux, leading to increased glutamine dependence and heightened sensitivity to glutaminase inhibition in cancer cells
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10.1186/s12876-016-0432-5 19 KlaunigJ
