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Proponents argue this maintains more stable tissue levels, though others find once-daily dosing equally effective with better compliance

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[DOI] [PubMed] [Google Scholar] 153.Turnbull AV, Ellershaw L, Masters DJ, et al

These preclinical data in mice support the hypothesis that EHS exposure can induce long-term physiological changes that may be linked to altered epigenetic profiles

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(Peptide Sciences) Comparative advantage and specificity Researchers note that many senolytics suffer from off-target cytotoxicity (i.e., they kill healthy cells too)