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407 The diterpene titer was first boosted through overexpression of rate-limiting enzymes in the MEV pathway and minimizing loss of isoprenyl precursors to primary metabolism

Discussion Metabolism reprogramming has gained much attention since cancer cells have the ability to rewire metabolism to promote cell survival in response to environmental stress [27, 28]

A standard curve with known GSH concentrations was used to calibrate all the results

Data distribution was initially assessed using the ShapiroWilk normality test

10.1089/acm.2006.12.881 Summary Keywords vitamin B12, efficacy, bioavailability, therapeutic approaches, meta-analysis, cobalamin Citation Mazur M, Ndokaj A, Salerno C, Vallone J, Ardan R, Bietolini S, Carrouel F, Wilk A, Sarig R, Ottolenghi L and Bourgeois D (2025) Efficacy of sublingual and oral vitamin B12 versus intramuscular administration: insights from a systematic review and meta-analysis

The cost is 35 for a single injection