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Antioxidants, including vitamin C, vitamin E, and Coenzyme Q10, play a critical role in protecting cells from oxidative stress (106, 107)

doi: 10.1091/mbc.9.5.1037

NAC also acts as a potent anti-inflammatory and antioxidant, directly scavenging reactive oxygen species (ROS) and regulating the redox state by maintaining the thiol pool being a precursor of cysteine (an essential substrate for glutathione synthesis)

In Proc 2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) (San Diego, CA, USA, IEEE, 2019) 303310

ICB therapy counteracts tumor-induced immune suppression by inhibiting immune checkpoint molecules such as PD-1/PD-L1 and CTLA-4, thus activating effector T cells and reinstating their antitumor functionality (Morad et al., 2021)

[12] Glutathione deficiency can contribute to age-related health problems