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Remarkably, specific domains within GR exhibited discernible patterns of positive and negative correlation, exemplified by residues 400-420 (Fig

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Evaluation of the Neuroprotective Effect of Cannabinoids in a Rat Model of Parkinson's Disease: Importance of Antioxidant and Cannabinoid Receptor-independent Properties

Besides, PROTAC often exerts its function via event-driven mode of action rather than occupancy-driven mode of action of traditional small molecule inhibitors, which suggests that this technology does not require high-affinity binding

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This lipid conjugation promotes reversible binding to serum albumin in experimental systems, which contributes to increased molecular stability and extended circulation time in research settings