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In addition, an in vivo shRNA library screen and validation using CRISPR induced gene deletion revealed that the loss of several p53-regulated DNA repair genes can markedly accelerate c-MYC-driven lymphomagenesis and the removal of Mlh1 , a key gene involved in MMR, can even on its own promote spontaneous tumour development [58]

Nature 546 , 118123 (2017)

Park JH, Lee SH, Chung IM, et al

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It is considered a research peptide and not approved for general medical use

The research briefs distill what the literature actually shows, where the gaps remain, and how our lots are verified before shipment," said Samuel Yanner, Director of Scientific Operations at Umbrella Labs