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Indicates that no adverse fetal effects have been observed at normal doses and that pyridoxine is considered safe and often beneficial in pregnancy

Based on evidence from clinical studies, the USPHS, AAP, and ACOG recommend a folic acid intake of 0.4 mg/day PO from food and/or supplements in females during the child-bearing years, and 0.6 mg PO daily throughout pregnancy

Wall, ., Food and Nutrition Guidelines for Healthy Adolescents

& Nasser, S

[9] Visual disturbances have been reported in patients with Leber hereditary optic neuropathy, and rapid B12 administration may precipitate optic nerve atrophy in this genetically predisposed population, mandating extreme caution or alternative therapy

You follow a vegan or vegetarian diet and need to supplement to meet your needs