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SIRT3 lysine deacetylase inhibitors specifically target SIRT3 without affecting its structurally similar counterparts, SIRT1 and SIRT2 185,186

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Briefly, cells were incubated with EdU and counterstained with DAPI, followed by visualization under a fluorescence microscope (Leica)

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It is used in the management of chemotherapy-induced nausea and vomiting among cancer patients (Machado Rocha et al., 2008) and for relief of spasticity in multiple sclerosis patients (Sastre-Garriga et al., 2011)

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