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Nature 556(7699):113117 [DOI] [PMC free article] [PubMed] [Google Scholar] Mitsuishi Y, Taguchi K, Kawatani Y, Shibata T, Nukiwa T, Aburatani H, Yamamoto M, Motohashi H (2012) Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming

Therefore, targeting the HIF1-c-MYC-PGC1 pathway enhances thermogenesis in beige adipose tissue, thereby providing a potential therapeutic strategy to mitigate obesity and metabolic disorders associated with high-fat diets [142]

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TRIM25, Tripartite motif-containing 25

doi: 10.3390/antiox12030655