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In hypertension, aberrant DNA methylation affects genes involved in vascular remodeling, such as At1b and Scnn1a, influencing blood pressure regulation
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Gene delivery barriers One of the most noticeable aspects of an effective gene therapy is the bypassing of gene delivery barriers, which can be categorized into intracellular and extracellular barriers [32], as shown in Table 1
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Our work suggests caution if the PT2385 inhibitor is used in an adjuvant setting with known chemotherapeutics that rely on ROS generation
