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Phase 2 trial data (NEJM, 2023) reported a mean body weight reduction of approximately 24% over 48 weeks at the highest dose, though larger Phase 3 trials are needed to confirm these findings

Dehydration: Creatine pulls water to the muscles while caffeine creates a slight diuretic effect

[DOI] [PubMed] [Google Scholar] Vittorelli A, Gauthier C, Michoudet C, Baverel G

2020 Auswirkungen einer L-Carnitin-Supplementierung auf den Gewichtsverlust und die Krperzusammensetzung Yarizadh et al

It has been reported that acetyl-L-carnitine nutrional supplements might be better absorbed by the body and therefore have better pharmacological effects as a dietary supplement

Previous evidence has indicated that calcitonin gene-related peptide (CGRP) and cytokines might play a role in the pathogenesis of migraine (159161)