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Chemotherapeutics may also alter the dynamics of mitochondrial fission and fusion

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The acetyl group distinguishes ALCAR from standard L-carnitine in two critical ways: it allows ALCAR to cross the blood-brain barrier efficiently, and it provides an acetyl group that can be donated to choline to form acetylcholine, the primary neurotransmitter of the cholinergic system

Based on these findings, we investigated whether palmitoyl-L-carnitine-induced tau phosphorylation depends on the activities of GSK-3, CDK5, and calpain
