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Accumulated toxic aldehydes in the liver can be effectively metabolized by mitochondrial aldehyde dehydrogenase 2 (ALDH2), thereby alleviating various liver diseases

(3) Notably, only 53.8% of those prescribed a GLP-1 agonist in 2022 had a history of type 2 diabetes, highlighting a shifting clinical paradigm in which these agents are now widely used for obesity management and related metabolic disorders

Thus, the antioxidant GPx-1 has been studied for its effect in modulating processes in which oxidants play an essential role, including normal cellular growth and proliferative responses

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