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The hemolysis is this condition is due to a fragmentation anemia from thrombosis in the renal vasculature (extravascular hemolysis), which causes concurrent acute renal failure (likely hypoxic injury) and thrombocytopenia (platelet consumption)

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The accumulation of these PL-PUFA-OOH molecules disrupts the integrity and fluidity of the cell membrane, ultimately leading to membrane rupture, the release of the cellular contents and cell death (18)

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Many skin diseases, including skin aging, are characterized by a common occurrence of chronic low-grade inflammation (145, 146)

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