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The ability to catalytically convert GSH into GSSG inside the cancer cells was assessed upon determination of the levels of GSH and GSSG after treatment
See HB4616 and HB4617 (2023)
Rovin S, Costich ER, Gordon HA
The lessons from their application in epilepsy and pain, combined with emerging genetic and optogenetic evidence, strongly support their continued investigation as a viable strategy for tinnitus treatment
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Increased levels of free zinc could serve as a co-stimulus for the upregulation of NF-B produced by LMP1 or CD40 signaling, as the intracellular increase in zinc induces the expression of MTs, which elevates the DNA-binding activity of NF-kB [332, 333]
