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IGF-1 LR3's modifications reduce its affinity for IGFBPs by approximately 1,000-fold

Apoferritin, the iron-depleted form of ferritin, is composed of 24 self-assembled subunits that form a spherical nanocage with a diameter of approximately 12 nm, featuring an internal cavity of 8 nm capable of encapsulating drugs, thereby constituting a ferritin drug carrier (FDC)

[DOI] [PubMed] [Google Scholar] 75.Sands B.E., DHaens G., Clemow D.B., Irving P.M., Johns J.T., Gibble T.H., Abreu M.T., Lee S.D., Hisamatsu T., Kobayashi T., et al

recommended storage below -18C desiccated, with reconstituted solutions viable at 4C for 27 days

GRAS Designation & Food Substance Classification In 2023, AOD-9604 received "Generally Recognized as Safe" (GRAS) designation from the FDA when submitted as a food substance or dietary supplement ingredient

3b and Table S14)