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The active components glycyrrhizin, glycrrhetinic acid, and glycyrrhizic acid in licorice root extracts were found to prevent the death of neuronal cells caused by amyloid- peptide present in plaques, thus alleviating symptoms of Alzheimers disease [58]

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Immunostaining of brain tissue for Iba1 and GFAP revealed that microglia and astrocytes were markedly activated in GCLC-KO mouse brains (Fig

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