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Here, through a proteomic screen of serum from AQP4-IgG-positive NMOSD patients and a control cohort, we observed a significant downregulation of Insulin-like growth factor 2 (IGF-2) in the serum of AQP4-IgG-positive NMOSD patients and correlated with disease severity
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The temporal dynamics of 5-amino-1MQ's cellular effects reveal sophisticated regulatory mechanisms that extend well beyond immediate enzyme inhibition
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