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These exosomes upregulated Wnt3a, p-GSK-3 (Ser9), and -catenin, activated Wnt/-catenin signaling, upregulated Bcl-2 and cyclin D1, inhibited Bax expression and caspase3 activity, antagonized I/R-induced cardiomyocyte apoptosis, and increased the cell survival rates

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What does compound heterozygous mean

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A., Rubin, B

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NLRP3 inflammasome estimation in gene expression studies using semi-quantitative PCR In this procedure, 100 mg of whole hippocampal tissue was mixed with 1 ml of TRIzol and allowed for tissue lysis

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However, under oxidative stress or pathological conditions like AGEs (72), Nrf2 is activated and translocated to the nucleus, initiating the expression of antioxidant genes such as GPX4, which are essential for reducing lipid peroxidation and delaying ferroptosis (73)

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