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Larger randomized trials are ongoing

The variability in measurements in this field of study may be due to several factors, such as the relationship between the increase in the Arg/asymmetric dimethylarginine ratio and the improvement of FMD [78], or due to the reduction in NO production with increasing asymmetric dimethylarginine levels and aging-related endothelial dysfunction

10.1016/j.bbadis.2012.12.001 94 LeeT.TakamiY.YamadaK.KobayashiH.HasegawaY.SasaiH.et al (2019)

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Exercise, as a non-pharmacological intervention, has demonstrated significant potential in the treatment of ALD