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Risk of bias assessment was performed using the Cochrane Risk-of-Bias tool for randomized trials

MSM is an excellent dietary source of bioavailable organic sulfur

Ferroptosis, a recently identified and iron-dependent cell death, differs from other cell death such as apoptosis, necroptosis, pyroptosis, and autophagy-dependent cell death

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flavonoids), showing weak prooxidant properties that may boost cellular antioxidant systems and thus act as preventive anticancer agents