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Different from short and medium-chain fatty acids that can enter the mitochondria directly, long-chain fatty acids are first converted to acyl-coA in the cytosol and must be transported by the carnitine shuttle through a multi-step process (Fig

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Overexpression of Sb9 has been detected in a variety of cancers, including low grade prostate cancer (102), cervical cancer (101), nasopharyngeal carcinoma (116), glioma (117), non-small cell lung carcinoma (118), breast cancer (119), acute lymphoblastic leukemia (120), Hodgkin lymphomas and non-Hodgkin lymphomas (95, 121)

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