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Intraoperative radiation therapy (IORT) is external radiation that is delivered to the tumor during a surgical procedure and is especially applicable to cancers deep inside the body (ACS 2014a

BBB, Bloodbrain barrier

Assessments of steady-state ATP levels in cells from ME/CFS patients showed conflicting results: decreases were seen in neutrophils, peripheral blood mononuclear cells (PBMCs) and primary skeletal muscle cell cultures [52, 105, 106], while elevated ATP levels were also observed in PBMCs, albeit attributed to nonmitochondrial ATP production [107]

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Adverse Reactions/Side Effects Oxalate, urate, or cystine renal stones causing renal tubular obstruction, characterized by costovertebral pain or lower back pain, can occur following large doses of ascorbic acid

Studies show core biological changes, including reduced NK cell function, activation of the NLRP3 inflammasome, altered interferon and cytokine signaling, and evidence of mitochondrial and metabolic dysfunction (lactate/pyruvate, haptoglobin)