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How do I know if my dog needs B12? Signs of deficiency B12 deficiency can manifest in several ways that affect your dogs overall well-being: Fatigue and lethargy: Reduced energy conversion means less pep in their step

So, these are much safer B12 values: As Sally and Jeffrey note: At this time, we believe normal serum B12 levels should be greater than 550 pg/ml

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Certain people may be at a higher risk of developing a vitamin B12 deficiency, including: Adults age 65 and older, often due to pernicious anemia, atrophic gastritis, and reduced production of enzymes People with pernicious anemia, an autoimmune condition that may cause gastric atrophy People with gastrointestinal disorders (like celiac disease and inflammatory bowel disease) that affect nutrient absorption Anyone who has had bariatric or gastrointestinal surgery Vegetarians and vegans (B12 is only found in animal-based foods) Breastfed infants of vegan mothers If left untreated, a deficiency in B12 can lead to nerve damage

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Reasons why mitochondria might be impaired or damaged include: Aging Inadequate diet Poor sleep Lack of exercise Genetics Heavy and toxic metals Pollutants Free radicals Prescription drugs Alcohol There are many conditions that are caused or made worse by mitochondrial dysfunction, such as the following per Pizzorno (2014): Early aging Amyotrophic lateral sclerosis Alzheimers disease Autism Cardiovascular disease Chronic fatigue syndrome Dementia Diabetes Huntingtons disease Migraine headache Parkinsons disease A great way to directly influence the health of our mitochondria is through the use of peptides