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Investigating curcumin anti-cancer effects through drug delivery system The therapeutic efficacy of curcumin, however, is restricted by its poor solubility, low absorption from the gut, rapid metabolism, and systemic elimination

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[DOI] [PubMed] [Google Scholar] 84.Chang A, Staugaitis SM, Dutta R, Batt CE, Easley KE, Chomyk AM, Yong VW, Fox RJ, Kidd GJ, Trapp BD

10.1016/j.biomaterials.2022.121428 23 Shimizu-SasamataM.KanoT.RogowskaJ.WolfG

Intervention of GPX4 blocks iron autophagy induced by MT1G overexpression MT1G overexpression promotes iron autophagy in GC cell lines by intervening in the GPX4/SQSTM1 axis

Handl J, Capek J, Majtnerova P et al (2019) Transient increase in cellular dehydrogenase activity after cadmium treatment precedes enhanced production of reactive oxygen species in human proximal tubular kidney cells