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Vitamin B12 effectiveness in the management of hospitalized COVID-19 and its clinical outcomes and complications: a randomized clinical trial

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downstream activation of JAK-STAT5 signaling in liver confirmed as primary mediator Significance : Demonstrates that pituitary-level GH stimulation produces sustained downstream IGF-1 responses with potential applications in research on anabolic signaling, bone metabolism, and tissue repair Limitations : IGF-1 data from CJC-1295 DAC studies
