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This led to an increase in short-chain fatty acid levels, activation of AMPK, and regulation of lipid metabolism genes such as ACOX1, ACC, and FASN, ultimately reducing blood lipid levels (223)

Gershon MD (2022) The Shaggy Dog Story of Enteric Signaling: Serotonin, a Molecular Megillah

However, T2DM patients with hypertension may have higher incidence of retinal vascular leakage compared to T1DM patients, mediated by elevated endothelin-1 (ET-1) and vascular cell adhesion molecule-1 (VCAM-1) expression (84, 85)

Erdel, F

Renal Manifestations of Fabry Disease: A Narrative Review

Anti-Alzheimer's drug, donepezil, markedly improves long-term survival after chronic heart failure in mice