glutathione concentration in cancer cells Excessive intake contributes to chemotherapy resistance breast cancer: a propensity score matching analysis | World Journal of Surgical Oncology Glutathione Depletion and Stalwart Anticancer

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Pasker, R

A decrease in the expression of the pro-ferroptotic proteins ACSL4, TFR1, and VDAC2/3 and a decrease in dihydroethidium (DHE) fluorescence, iron, malondialdehyde (MDA), and myeloperoxidase (MPO) were further observed in metformin-treated mice

Since Burkitt's Lymphoma (BL) cells display limited uptake capacity for cystine, and are thus prone to oxidative stress-induced cell death, we stably expressed the substrate-specific subunit of system xc, xCT, in HH514 BL cells

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