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Acute psychological stress (Trumpff et al., 2019), major depression (Lindqvist et al., 2018), and intense physical activity (Stawski et al., 2017) modify mitokines production and increase circulating cf-mtDNA

In critical care scenarios, metabolic demand for zinc skyrockets

[DOI] [PMC free article] [PubMed] 46.Lewitt PA

4.7 Genetic and epigenetic factors Genetic and epigenetic factors also influence the susceptibility to metabolic syndrome

The normal course of untreated hyperuricemia, leading to progressive urate crystal deposition, begins with uric acid urolithiasis (urate kidney stones) and progresses to acute gouty arthritis, then intercritical gout and chronic tophaceous gout

van der Aart-van der Beek AB, Apperloo E, Jongs N, et al