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Targeted deletion of Sec-tRNA [Ser]Sec ( Trsp ) gene in osteochondroprogenitor cells from embryonic stage caused the depletion of selenoproteins in skeletal systems, causing growth retardation, abnormalities in the epiphyseal growth plate, delayed endochondral ossification, and chondronecrosis, which recapitulated the major pathological features of KBD 73

These findings suggest that TNF- binding to TNFR2 may lead to necroptosis of astrocytes under certain conditions

[DOI] [PubMed] [Google Scholar] 63.Zupani ., Lavri Z., Kristl J

[Abstract]2024 May 21

The formation of the autophagosome requires the expansion of its membrane, a process driven by autophagy-related genes known as Atgs (Takeshige et al., 1992)