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Pharmacokinetic investigations revealed that methylthioadenosine was more absorbed and had a longer residence time in the SLNs, increasing its bioavailability and targeted delivery in the brain
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doi: 10.1016/j.bbamcr.2008.05.007

Nebulizer For nanoparticle formulation in liquid solution or suspensions, favorable MMAD and FPF of aerosolized liquid droplets can be achieved by choosing appropriate inhalation devices (e.g., jet nebulizers, vibrating mesh nebulizers) [175]