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Upon HGF binding to MET, the receptor is activated by dimerization

TenhunenABvan der HeijdenJSkorupPMaccaranaMLarssonALarssonAet al

FN receptors are located in every tissue that originates from the three primary germ layers and are therefore considered to modulate embryogenic cellular migration and anchoring (24), which suggested the FN signaling may mediate the cellular-ECM signal transduction that may, in turn, modulate LOX secretion

doi: 10.1074/jbc.M111.263020

This process promotes skin tightening and remodeling from within, resulting in a smoother, more youthful complexion