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Germline and somatic mutations in METs kinase domain leading to constitutive activation are seen in renal papillary carcinoma, childhood hepatocellular carcinoma and colorectal cancer [10,11,12], whilst intronic mutations leading to an exon 14 deleted splice variant are seen in non-small cell lung cancer (NSCLC) [6]

Prevalence of obesity and severe obesity among adults: United States, 2017-2018