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Given that both CGAS/STING activation and reduced GPX4 levels have been observed in various neural cells in depression models, their interaction may contribute to ferroptosis and pathological injury in the hippocampus and PFC (Liu et al., 2022
D., Molofsky, A
10.1016/s1097-2765(04)00211-4 Mol
Huang Q, Su H, Qi B et al (2021) A SIRT1 activator, ginsenoside Rc, promotes energy metabolism in cardiomyocytes and neurons
Yao et al., 2017b
doi: 10.1371/journal.pgen.1006907 179
