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IGF-1 has been shown to upregulate the expression of MMP-9 and uPA, as well as MMP-9 activity, in breast carcinoma cells, though this regulation may be cell-type specific [117,118,119]

Mayr A, Schlosser M, Grober N et al (2007) GAD autoantibody affinity and epitope specificity identify distinct immunization profiles in children at risk for type 1 diabetes

Targeting strategies for chemotherapy-induced peripheral neuropathy: does gut microbiota play a role

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Harmful molecules are called reactive oxygen species (ROS) and the damage they cause is called oxidative stress

et al., Eur J Endocrinol