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developed inhalable IL11siRNA nanoparticles using PEI modified with 4guanidinobenzoic acid [89]
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A change in either CL or Vd has a very different effect on the concentration-time profile (Figure 5, A and B), but in each case, the dosing interval should be doubled (Figure 5C)

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Alam MK, Alqhtani NR, Alnufaiy B, et al
CrossRef Prognosis of pancreaticoduodenectomy in octogenarians for pancreatic ductal adenocarcinoma with propensity score matched analysis HyeJeong Jeong, Soo Yeun Lim, Hyun Jeong Jeon, So Jeong Yoon, Hongbeom Kim, In Woong Han, Jin Seok Heo, Sang Hyun Shin ANZ Journal of Surgery.2023
