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2,3 IVD Structure IVDs are fibrocartilaginous pads that primarily serve a mechanical role transmitting physiologic load as well as providing flexibility to the spine, thus allowing flexion, extension, and lateral bending

Dihexa reversed cognitive deficits induced by scopolamine (an anticholinergic agent) in rodent models, suggesting relevance to cholinergic aspects of cognitive impairment

Gastrointestinal: Hepatitis (including cholestatic jaundice and hepatic necrosis), elevation of serum transaminase and bilirubin, pseudomembranous enterocolitis, pancreatitis, stomatitis, glossitis, nausea, emesis, abdominal pain, diarrhea, anorexia

This is why self-directed dosing is risky and why provider-guided treatment is the safer route

Following incubation, beads were washed once with cold KPBS (pH=7.25) before being incubated in 200 l transport buffer (KPBS+10 mM HEPES + 0.5 mM EGTA) at room temperature containing indicated doses of [ 13 C 2 , 15 N]-GSH (Cambridge Isotope Laboratory, CNLM-6245-50) for the indicated times